# The pathogenesis of cardiovascular diseases #
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## Cardiovascular Disease-Video ##
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The pathogenesis of cardiovascular diseases: A view into the depth of the human system
This is below the world and the lifestyle of people is changing, the prevalence of cardiovascular disease (CVD) worldwide. These diseases are among the leading causes of death and represent a serious challenge for the health system. But what exactly is in the body the wrong way, if such a condition develops? What are the mechanisms behind the pathogenesis of this life-threatening conditions?
The basis of many cardiovascular diseases is often a combination of genetic predisposition and environmental influences. The pathogenesis of the disease usually begins with subtle changes in the vascular system — for example, with the formation of atherosclerosis plaques. These Plaques are caused by the deposition of lipids, in particular LDL‑cholesterol in the Intima of the arteries.
The process works as follows:
Endothelial damage. The endothelium — the inner lining of the blood vessels caused by factors such as increased blood pressure, Smoking, hyperglycemia, or inflammatory processes.
Lipid storage. LDL particles to penetrate into the vessel wall and become oxidized. This is a local inflammatory response triggers.
Immune response. Macrophages migrate to the sites of Injury and to phagocytize the oxidized lipids. You transform into foam cells, the part of the picture ends Plaque.
Plaque formation and progression. The Plaque grows and can restrict the vascular Lumina. In later stages it can lead to cracking of the Plaque, which leads to thrombus formation.
Consequences for the cardiovascular System. Due to the restriction of blood flow to Ischemia — for example a heart attack or stroke.
In addition to atherosclerosis, further pathophysiological mechanisms play a role:
High Blood Pressure (Hypertension). Due to increased vascular resistance and increased cardiac output, an Overload of the heart arises. In the long term, this leads to left heart enlargement and congestive heart failure.
Inflammatory processes. Chronic inflammation, such as obesity or type 2 Diabetes mellitus, promote the development and Progression of CVD.
Metabolic disorders. Insulin resistance and dyslipidemia create an environment in which vascular damage may occur easier.
Prevention as the key to combating
The findings on the pathogenesis of the show: Many of the risk factors can be influenced. A healthy diet, regular physical activity, the lack of Smoking, and stress management can slow down the development of cardiovascular diseases significantly or even prevent it.
Medical diagnosis — for example, by measurement of blood pressure, cholesterol tests and blood sugar controls — makes it possible to identify high-risk patients at an early stage and to take care of specifically.
Conclusion
The pathogenesis of cardiovascular diseases is a complex, multi-stage event that occurs on a molecular, cellular and systemic level. But just because we now know so much about these processes, we have effective tools to prevent disease and mitigate its effects. The future is, therefore, not only therapy, but, above all, the prevention for a healthier life and a healthier society.
If you want, I can make a specific section in more detail, or to install additional aspects (such as specific diseases, or the latest research and results)!
> Ang mga modernong gamot sa pag-imprenta ay hinahati sa 10 iba't ibang grupo ayon sa kanilang mekanismo ng pagkilos. Pagkatapos suriin ng doktor ang mga reklamo ng pasyente at ang resulta ng mga pagsusuri, nagrereseta siya ng isa o higit pang gamot, na hindi dapat baguhin nang mag-isa. Ang mga gamot sa puso at daluyan ng dugo ay hindi kabilang sa mga puwedeng irekomenda sa kaibigan. Ang maling desisyon ay maaaring magdulot ng malungkot na kahihinatnan. Lahat ng gamot na pampababa ng presyon ng dugo ay kailangan ng reseta. Sa artikulong ito, tinitingnan natin ang kanilang modernong klasipikasyon base sa mga aktibong sangkap at sa paraan ng epekto nito sa katawan.

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<a href="https://notes.rabjerg.de/s/Bk5r9t_Mzx">Cardiovascular Disease-Video</a> ** The pathogenesis of cardiovascular diseases **.
Scientific Text to the Video on cardiovascular diseases
Title: cardiovascular disease: causes, risk factors, and prevention
Introduction
Cardiovascular disease (CVD) is the most common cause of death. According to recent statistics, approximately 17.8 million deaths in 2017, cases of cardiovascular problems due to the corresponds to an average of 32% of all deaths worldwide. In Europe and particularly in Germany, HKE the mortality statistics. This Video is intended to give an Overview of the most important aspects of this disease group: of the main causes of the risk factors to possible prevention measures.
Main part
Occurrence and importance
The high prevalence of cardiovascular diseases makes it a Central theme of modern medicine. In the WHO European region, a total of 4.3 million cardiovascular-related were registered in 2016, deaths, one of which is 2,1 million to an unbalanced diet are due. In the EU, about 900000 cases accounted for.
Risk factors
Several factors increase the risk for development of CVD:
Hypertension: A long-lasting increase in blood pressure charged to the heart and blood vessels.
Unbalanced diets, Too much salt, saturated fat and sugar contribute to the development of atherosclerosis and other cardiovascular disorders.
Overweight and obesity: studies show that people with a BMI of 25 to 27.5 the cardiovascular mortality risk of 11% and a BMI of 27.5 to 30 by 35% compared to normal-weight is increased. The Framingham heart study also found that being Overweight at the age of 40 years reduces the life expectancy of an average of three years; in the case of obesity, there are even six and a half years.
Smoking: Worldwide, approximately 10% of cardiovascular disease is attributed to Smoking. The Quit Smoking (from about the 30. Years of age) reduces the risk to the level of non-smokers. Passive the emergence of CVD promotes Smoking, especially in children.
Diabetes mellitus: high blood sugar levels damage the blood vessels and increases the risk of heart attacks and strokes.
Lack of exercise: Regular physical activity strengthens the cardiovascular System and lowers the risk of disease.
Gender differences
Men are affected more frequently and often in recent years, diet-related cardiovascular diseases. Women show a significantly increased risk after the age of 50. Age, partly because of the hormonal changes in the Menopause together.
Diagnosis and treatment
Timely diagnosis allows for an effective treatment that can slow the progression of the disease or stop it. Important diagnostic procedures are:
ECG (electrocardiogram),
Ultrasound examination of the heart (echocardiography),
Stress tests
Laboratory Tests (Lipid Spectrum Of Blood Sugar).
Therapeutic measures include medications (e.g., blood pressure-lowering, cholesterol-lowering drug) and, if necessary, surgical interventions (e.g., Bypass surgery, Stent Implantation).
Prevention
The prevention of cardiovascular disease is based on a healthy life style:
a balanced diet with lots of fruits, vegetables, fiber, and unsaturated fatty acids;
regular physical activity (at least 150 minutes of moderate load per week);
Waiver of Smoking and excessive alcohol consumption;
Weight control and blood pressure measurement;
Stress management and adequate sleep.
Conclusion
Cardiovascular diseases are a serious health challenge with a high risk of death. However, the individual risk by living a healthy lifestyle can be significantly reduced. Education and prevention play a Central role. The Video conveys the most important information to raise the awareness of citizens for the topic and to give you a set of practical recommendations.
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- [x] <a href="https://notes.srcf.net/s/cNDwSEPR6">2 diseases of the circulatory System</a>
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## 2 diseases of the circulatory System ##
Protect your cardiovascular System: Identify the risks in a timely manner!
Your heart and your circulatory system is working every day, tirelessly — give them the attention they deserve! Two of the most common diseases of the cardiovascular system, which can greatly affect your life, are:
Coronary heart disease (CHD)
In this disease, the coronary arteries become narrow due to deposits (Placken), which restricts the blood flow to the heart. Typical symptoms are chest pain (Angina), shortness of breath, and fatigue. Without treatment, it can lead to a heart attack.
High Blood Pressure (Hypertension)
Many people live for years with elevated blood pressure, without realizing it. Permanently high blood pressure strains the heart, kidneys and blood vessels and increases the risk for stroke and heart attack.
What can you do?
Early detection saves lives! Regular checkups with your doctor can help to detect these diseases early and treat them.
Practical steps to a healthier heart:
A healthy diet with lots of fruits, vegetables and foods rich in fiber
Regular physical activity (at least 30 minutes per day)
Waiver of nicotine and moderate use of alcohol
Stress management and adequate sleep
Regular monitoring of blood pressure and blood fat
Appointment for a heart Check-Up investigation back up!
You speak with your physician or cardiologist, and take the Chance your heart‑circuit to protect the System in the long term. Invest in your health — your heart will thank you!
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Your health is our concern.